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Why use a Drummond Self-Locking Filter in Your Pipet-Aid?

In order to provide a fail-safe, one-time check valve for Pipet-Aid pipettors, Drummond pioneered the use of a “self-locking” dual layer filter composed of one hydrophobic membrane and one hydrophilic membrane located in the nosepiece. With a dual layer membrane, when the filter is challenged with an aqueous solution, the hydrophobic layer prevents liquid from entering the handle and the wetted hydrophilic layer restricts the flow of air which locks the Pipet-Aid from further use. When this happens, the user must replace the filter and clean the other wetted parts, thus protecting the Pipet-Aid as well as the integrity of subsequent dispensings.

The specifications for the Drummond filter are .8 µm for the hydrophilic layer and .8 µm for the hydrophobic layer. Most competitive pipetting units use a single layer hydrophobic membrane filter with ratings of either .22 µm and .45 µm. These filters protect the handle only. If challenged with an aqueous solution, the filter will prevent the liquid from entering the handle; however, it can be subsequently blown out and pipetting can be continued. This action creates an aerosol generator just above the pipet and all subsequent dispensings are at risk of being contaminated. While the user may think he or she is sterilizing the air entering the pipet, they are in fact introducing contamination.

The most effective safety measure to prevent contamination is the cotton or fiber plug in each pipet. Even if a sterile filter is installed in a Pipet-Aid, the first time an aerosol comes in contact with the bottom membrane, the filter is rendered forever non-sterile. The only thing that prevents this from happening is the plug in the pipet itself which prevents aerosols from leaving the pipet and prevents them from entering. Drummond “self-locking” filters are supplied non-sterile because we believe there is no effective and practical method to maintain sterility in these devices.

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The New Nanoject III Is Now Available!

Nanoject II vs. Nanoject III Comparison

Both units utilize the same glass capillaries for pulling micropipettes. Due to the new improved method of securing the micropipette, smaller tips can be pulled and utilized on the Nanoject III. No O-rings to wear out. A micro “chuck” is used, and it simplifies attachment of the micropipette once backfilled with oil. The Nanoject III’s auto HOMING feature will eliminate the need to “rehome the unit as in the Nanoject II. This can reduce, if not totally eliminate, jamming of the plunger. Now available for the Nanoject II is the new Digital Control Box which has all the functionality of the original control box but now features a user friendly, easy to read touchscreen.

Product Name Nanoject II Nanoject III
Injection volumes 2.3 nL-69 nL 0.6 nL-999.9 nL
Rate of injection 46 nL/sec.& 23 nL/sec. only 1 nL/sec.-200 nL/sec.
Injection counter No Yes
Programmable multiple injections No Yes
Programmable frequency between injections No Yes
Auto HOMING of plunger No Yes
Micropipette I.D. size 10 µm minimum 2-3 µm minimum
Optional Footswitch Yes; inject only Yes; fill, empty and inject capability
Color, Touch Sensitive Keypad No; fill, empty, inject buttons only. Optional Digital Control Box Upgrade available Yes; multi screens
External computer interface Use of footswitch contact to inject. Injector has to be finished its injection at the speed rate of the Nanoject II before it will accept another pulse Use of a special opto-isolated input to allow the user to control injection rate and injection volume

Drummond Pipet-Aid® Controller Comparison Chart

Use this comparison chart to understand the difference between Drummond Pipet-Aid® Controller models and their useful features. This information will help you choose the best pipette controller to deliver the most accurate results for your intended applications.

Feature Other Pipette Controllers Portable Pipet- Aid® XP Pipette Controller Portable Pipet- Aid® XL Pipette Controller Pipet- Aid® Hood Mate® Pipette Controller
Cordless/Portable
3 Speed Aspiration & Dispensing X
Removable Stand X X
Use in hood/laminar flow cabinet X X
Weight 230g 214g 214g 122g